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Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data.
Chaudhry, Aqsaa; Chung, Git; Lynn, Adam; Yalvigi, Akshata; Brown, Colin; Ellens, Harma; O'Connor, Michael; Lee, Caroline; Bentz, Joe.
Afiliação
  • Chaudhry A; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
  • Chung G; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
  • Lynn A; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
  • Yalvigi A; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
  • Brown C; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
  • Ellens H; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
  • O'Connor M; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
  • Lee C; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
  • Bentz J; Departments of Biology (A.C., A.L., A.Y., M.O., J.B.) and Biodiversity, Ecology and Earth Sciences (M.O.), Drexel University, Philadelphia, Pennsylvania; Newcastle University, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, United Kingdom (G.C., C.B.); GlaxoSmithKline Pharmaceutic
Drug Metab Dispos ; 46(3): 279-290, 2018 03.
Article em En | MEDLINE | ID: mdl-29317410
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transporte Biológico / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Digoxina Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transporte Biológico / Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Digoxina Idioma: En Ano de publicação: 2018 Tipo de documento: Article