Preliminary Study for Measurement of Shear Stress and Hemocompatibility Using Commercialized Lab on a Chip.
J Nanosci Nanotechnol
; 18(2): 1123-1126, 2018 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-29448543
ABSTRACT
We have investigated the effect of flow rate on shear stress and in turn thrombus formation on a lab-on-a-chip with a microchannel that is suitable for cell culture and growth. Using a combination of Arduino UNO, Arduino Motor Shield, and a SERVO stepper motor, we created a pump system that closely mimics the in vivo conditions of the human body. With this system, we achieved continuous flow of blood and observed attached platelets at the bottom of the collagen coated microslide, confirming that with shear stress, thrombus formation increases.
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MEDLINE
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En
Ano de publicação:
2018
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Article