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High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.
Bueno, Oskía; Estévez Gallego, Juan; Martins, Solange; Prota, Andrea E; Gago, Federico; Gómez-SanJuan, Asier; Camarasa, María-José; Barasoain, Isabel; Steinmetz, Michel O; Díaz, J Fernando; Pérez-Pérez, María-Jesús; Liekens, Sandra; Priego, Eva-María.
Afiliação
  • Bueno O; Instituto de Química Médica (IQM,CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
  • Estévez Gallego J; Centro de Investigaciones Biológicas (CIB,CSIC), Ramiro de Maeztu 9, 28040, Madrid, Spain.
  • Martins S; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000, Leuven, Belgium.
  • Prota AE; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, 5232, Villigen, Switzerland.
  • Gago F; Department of Biomedical Sciences (Unidad Asociada IQM,CSIC) and Instituto de Investigación Quimica "Andrés M. del Río" (IQAR), University of Alcalá, Unidad Asociada CSIC, 28805 Alcalá de Henares, Madrid, Spain.
  • Gómez-SanJuan A; Instituto de Química Médica (IQM,CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
  • Camarasa MJ; Instituto de Química Médica (IQM,CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
  • Barasoain I; Centro de Investigaciones Biológicas (CIB,CSIC), Ramiro de Maeztu 9, 28040, Madrid, Spain.
  • Steinmetz MO; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, 5232, Villigen, Switzerland.
  • Díaz JF; University of Basel, Biozentrum, CH-4056, Basel, Switzerland.
  • Pérez-Pérez MJ; Centro de Investigaciones Biológicas (CIB,CSIC), Ramiro de Maeztu 9, 28040, Madrid, Spain.
  • Liekens S; Instituto de Química Médica (IQM,CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
  • Priego EM; Rega Institute for Medical Research, KU Leuven, Herestraat 49, B-3000, Leuven, Belgium.
Sci Rep ; 8(1): 4242, 2018 03 09.
Article em En | MEDLINE | ID: mdl-29523799
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Cicloexanonas / Moduladores de Tubulina Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Espanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Cicloexanonas / Moduladores de Tubulina Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Espanha