MiR-21 regulates the apoptosis of keloid fibroblasts by caspase-8 and the mitochondria-mediated apoptotic signaling pathway via targeting FasL.

Liu, Ying; Ren, Lihong; Liu, Wenjing; Xiao, Zhibo

Liu, Ying; Ren, Lihong; Liu, Wenjing; Xiao, Zhibo.

Afiliação

Liu Y; a Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200011, People's Republic of China.
Ren L; b Department of Plastic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, People's Republic of China.
Liu W; b Department of Plastic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, People's Republic of China.
Xiao Z; b Department of Plastic Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, People's Republic of China.

Biochem Cell Biol ; 96(5): 548-555, 2018 10.

Article em En | MEDLINE | ID: mdl-29527928

Assuntos

Caspase 8/metabolismo; Proteína Ligante Fas/metabolismo; Fibroblastos/metabolismo; Queloide/metabolismo; MicroRNAs/metabolismo; Mitocôndrias/metabolismo; Transdução de Sinais; Apoptose; Feminino; Fibroblastos/patologia; Humanos; Queloide/patologia; Masculino; Mitocôndrias/patologia

Palavras-chave

FasL; apoptose; apoptosis; chéloïde; keloid; miR-21; mitochondria-mediated apoptotic signaling pathway; voie de signalisation mitochondriale de l'apoptose

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / MicroRNAs / Caspase 8 / Proteína Ligante Fas / Fibroblastos / Queloide / Mitocôndrias Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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