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Hepatic-targeted RNA interference provides robust and persistent knockdown of alpha-1 antitrypsin levels in ZZ patients.
Turner, Alice M; Stolk, Jan; Bals, Robert; Lickliter, Jason D; Hamilton, James; Christianson, Dawn R; Given, Bruce D; Burdon, Jonathan G; Loomba, Rohit; Stoller, James K; Teckman, Jeffery H.
Afiliação
  • Turner AM; University of Birmingham, Birmingham, UK. Electronic address: A.M.Turner@bham.ac.uk.
  • Stolk J; Leiden University Medical Center, Leiden, The Netherlands.
  • Bals R; Saarland University Hospital, Homburg, Germany.
  • Lickliter JD; Nucleus Network, Melbourne, Victoria, Australia.
  • Hamilton J; Arrowhead Pharmaceuticals, Pasadena, CA, USA.
  • Christianson DR; Arrowhead Pharmaceuticals, Pasadena, CA, USA.
  • Given BD; Arrowhead Pharmaceuticals, Pasadena, CA, USA.
  • Burdon JG; Saint Vincent's Private Hospital, Melbourne, Australia.
  • Loomba R; University of California at San Diego, San Diego, CA, USA.
  • Stoller JK; Cleveland Clinic, Cleveland, OH, USA.
  • Teckman JH; St. Louis University School of Medicine, St. Louis, MO, USA.
J Hepatol ; 69(2): 378-384, 2018 08.
Article em En | MEDLINE | ID: mdl-29572094
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alfa 1-Antitripsina / Deficiência de alfa 1-Antitripsina / Terapêutica com RNAi / Cirrose Hepática Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alfa 1-Antitripsina / Deficiência de alfa 1-Antitripsina / Terapêutica com RNAi / Cirrose Hepática Idioma: En Ano de publicação: 2018 Tipo de documento: Article