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New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2).
Ribeiro, Carlos J A; Kankanala, Jayakanth; Shi, Ke; Kurahashi, Kayo; Kiselev, Evgeny; Ravji, Azhar; Pommier, Yves; Aihara, Hideki; Wang, Zhengqiang.
Afiliação
  • Ribeiro CJA; Center for Drug Design, Academic Health Center, University of Minnesota, Minneapolis, MN 55455, United States.
  • Kankanala J; Center for Drug Design, Academic Health Center, University of Minnesota, Minneapolis, MN 55455, United States.
  • Shi K; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, United States.
  • Kurahashi K; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, United States.
  • Kiselev E; Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
  • Ravji A; Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
  • Pommier Y; Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States.
  • Aihara H; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, United States.
  • Wang Z; Center for Drug Design, Academic Health Center, University of Minnesota, Minneapolis, MN 55455, United States. Electronic address: wangx472@umn.edu.
Eur J Pharm Sci ; 118: 67-79, 2018 Jun 15.
Article em En | MEDLINE | ID: mdl-29574079
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Fosfodiesterase / Diester Fosfórico Hidrolases / Ensaios de Triagem em Larga Escala Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Fosfodiesterase / Diester Fosfórico Hidrolases / Ensaios de Triagem em Larga Escala Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos