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A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
Nile, Aaron H; de Sousa E Melo, Felipe; Mukund, Susmith; Piskol, Robert; Hansen, Simon; Zhou, Lijuan; Zhang, Yingnan; Fu, Yue; Gogol, Emily B; Kömüves, László G; Modrusan, Zora; Angers, Stephane; Franke, Yvonne; Koth, Christopher; Fairbrother, Wayne J; Wang, Weiru; de Sauvage, Frederic J; Hannoush, Rami N.
Afiliação
  • Nile AH; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA.
  • de Sousa E Melo F; Department of Molecular Oncology, Genentech, South San Francisco, CA, USA.
  • Mukund S; Department of Structural Biology, Genentech, South San Francisco, CA, USA.
  • Piskol R; Department of Bioinformatics and Computational Biology, Genentech, South San Francisco, CA, USA.
  • Hansen S; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA.
  • Zhou L; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA.
  • Zhang Y; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA.
  • Fu Y; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA.
  • Gogol EB; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA.
  • Kömüves LG; Department of Pathology, Genentech, South San Francisco, CA, USA.
  • Modrusan Z; Department of Molecular Biology, Genentech, South San Francisco, CA, USA.
  • Angers S; Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada.
  • Franke Y; Department of Biomolecular Resources, Genentech, South San Francisco, CA, USA.
  • Koth C; Department of Structural Biology, Genentech, South San Francisco, CA, USA.
  • Fairbrother WJ; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA.
  • Wang W; Department of Structural Biology, Genentech, South San Francisco, CA, USA.
  • de Sauvage FJ; Department of Molecular Oncology, Genentech, South San Francisco, CA, USA.
  • Hannoush RN; Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA. hannoush.rami@gene.com.
Nat Chem Biol ; 14(6): 582-590, 2018 06.
Article em En | MEDLINE | ID: mdl-29632413
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Receptores Frizzled / Intestinos Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Receptores Frizzled / Intestinos Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos