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Design, (Radio)Synthesis, and in Vitro and in Vivo Evaluation of Highly Selective and Potent Matrix Metalloproteinase 12 (MMP-12) Inhibitors as Radiotracers for Positron Emission Tomography.
Butsch, Viktoria; Börgel, Frederik; Galla, Fabian; Schwegmann, Katrin; Hermann, Sven; Schäfers, Michael; Riemann, Burkhard; Wünsch, Bernhard; Wagner, Stefan.
Afiliação
  • Butsch V; Department of Nuclear Medicine , University Hospital Münster , Albert-Schweitzer-Campus 1, Building A1 , 48149 Münster , Germany.
  • Börgel F; Institute of Pharmaceutical and Medicinal Chemistry , University of Münster , Corrensstraße 48 , 48149 Münster , Germany.
  • Galla F; Institute of Pharmaceutical and Medicinal Chemistry , University of Münster , Corrensstraße 48 , 48149 Münster , Germany.
  • Schwegmann K; European Institute for Molecular Imaging , University of Münster , Waldeyerstraße 15 , 48149 Münster , Germany.
  • Hermann S; European Institute for Molecular Imaging , University of Münster , Waldeyerstraße 15 , 48149 Münster , Germany.
  • Schäfers M; Department of Nuclear Medicine , University Hospital Münster , Albert-Schweitzer-Campus 1, Building A1 , 48149 Münster , Germany.
  • Riemann B; European Institute for Molecular Imaging , University of Münster , Waldeyerstraße 15 , 48149 Münster , Germany.
  • Wünsch B; Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM) , University of Münster , 48149 Münster , Germany.
  • Wagner S; Department of Nuclear Medicine , University Hospital Münster , Albert-Schweitzer-Campus 1, Building A1 , 48149 Münster , Germany.
J Med Chem ; 61(9): 4115-4134, 2018 05 10.
Article em En | MEDLINE | ID: mdl-29660282

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Tomografia por Emissão de Pósitrons / Metaloproteinase 12 da Matriz / Inibidores de Metaloproteinases de Matriz Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Tomografia por Emissão de Pósitrons / Metaloproteinase 12 da Matriz / Inibidores de Metaloproteinases de Matriz Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha