Molecular basis of the skin barrier structures revealed by electron microscopy.
Exp Dermatol
; 27(8): 841-846, 2018 08.
Article
em En
| MEDLINE
| ID: mdl-29704884
ABSTRACT
The barrier function of skin is indispensable for terrestrial animals. This function is mainly carried out by the epidermis, more specifically by its granular and cornified layers. The major structural components associated with this function are the intercellular lipid layer, desmosomes, corneodesmosomes, tight junctions, cornified cell envelope and keratin filaments. In this review, we discuss the current knowledge of their ultrastructure, their molecular basis and their relevance to skin disease.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Fenômenos Fisiológicos da Pele
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Microscopia Eletrônica
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Japão