Defining the impact of melanopsin missense polymorphisms using in vivo functional rescue.

Rodgers, Jessica; Hughes, Steven; Pothecary, Carina A; Brown, Laurence A; Hickey, Doron G; Peirson, Stuart N; Hankins, Mark W

Rodgers, Jessica; Hughes, Steven; Pothecary, Carina A; Brown, Laurence A; Hickey, Doron G; Peirson, Stuart N; Hankins, Mark W.

Afiliação

Rodgers J; Nuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute, OMPI G, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Hughes S; Nuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute, OMPI G, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Pothecary CA; Nuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute, OMPI G, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Brown LA; Nuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute, OMPI G, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Hickey DG; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, West Wing, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Peirson SN; Nuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute, OMPI G, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Hankins MW; Nuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute, OMPI G, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

Hum Mol Genet ; 27(15): 2589-2603, 2018 08 01.

Article em En | MEDLINE | ID: mdl-29718372

Assuntos

Polimorfismo de Nucleotídeo Único; Células Ganglionares da Retina/fisiologia; Opsinas de Bastonetes/genética; Opsinas de Bastonetes/metabolismo; Animais; Dependovirus/genética; Regulação da Expressão Gênica; Humanos; Luz; Transdução de Sinal Luminoso; Camundongos Mutantes; Camundongos Transgênicos; Mutação de Sentido Incorreto; Pupila/fisiologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Ganglionares da Retina / Opsinas de Bastonetes / Polimorfismo de Nucleotídeo Único Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

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