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The PPARγ agonist rosiglitazone sensitizes the BH3 mimetic (-)-gossypol to induce apoptosis in cancer cells with high level of Bcl-2.
Li, Xinzhe; He, Jintao; Li, Bo; Gao, Min; Zeng, Yijun; Lian, Jiqin; Shi, Chunmeng; Huang, Yan; He, Fengtian.
Afiliação
  • Li X; Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Army Medical University (Third Military Medical University), Chongqing, China.
  • He J; Institute of Combined Injury, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
  • Li B; Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Army Medical University (Third Military Medical University), Chongqing, China.
  • Gao M; Chinese PLA 44 Hospital, Guiyang, China.
  • Zeng Y; Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Army Medical University (Third Military Medical University), Chongqing, China.
  • Lian J; Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Army Medical University (Third Military Medical University), Chongqing, China.
  • Shi C; Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Army Medical University (Third Military Medical University), Chongqing, China.
  • Huang Y; Institute of Combined Injury, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
  • He F; Cancer Center, Daping Hospital and Research Institute of Surgery, Army Medical University (Third Military Medical University), Chongqing, China.
Mol Carcinog ; 57(9): 1213-1222, 2018 09.
Article em En | MEDLINE | ID: mdl-29856104
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gossipol / Apoptose / Proteínas Proto-Oncogênicas c-bcl-2 / PPAR gama / Rosiglitazona / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gossipol / Apoptose / Proteínas Proto-Oncogênicas c-bcl-2 / PPAR gama / Rosiglitazona / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China