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A single amino acid substitution in the NS4B protein of Dengue virus confers enhanced virus growth and fitness in human cells in vitro through IFN-dependent host response.
Bui, Thuy Thu; Moi, Meng Ling; Nabeshima, Takeshi; Takemura, Taichiro; Nguyen, Trang Thu; Nguyen, Linh Ngoc; Pham, Hang Thi Thu; Nguyen, Thi Thu Thuy; Manh, Dao Huy; Dumre, Shyam Prakash; Mizukami, Shusaku; Hirayama, Kenji; Tajima, Shigeru; Le, Mai Thi Quynh; Aoyagi, Kiyoshi; Hasebe, Futoshi; Morita, Kouichi.
Afiliação
  • Bui TT; 1​Department of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
  • Moi ML; 2​Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
  • Nabeshima T; 1​Department of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
  • Takemura T; 1​Department of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
  • Nguyen TT; 3​NIHE-Nagasaki Friendship Laboratory, Nagasaki University, Hanoi, Vietnam.
  • Nguyen LN; 3​NIHE-Nagasaki Friendship Laboratory, Nagasaki University, Hanoi, Vietnam.
  • Pham HTT; 4​Department of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
  • Nguyen TTT; 4​Department of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
  • Manh DH; 4​Department of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
  • Dumre SP; 2​Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
  • Mizukami S; 5​Department of Immunogenetics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
  • Hirayama K; 5​Department of Immunogenetics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
  • Tajima S; 6​Department of Clinical Product Development, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
  • Le MTQ; 5​Department of Immunogenetics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
  • Aoyagi K; 7​Department of Virology 1, National Insitute of Infectious Diseases, Tokyo, Japan.
  • Hasebe F; 4​Department of Virology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
  • Morita K; 8​Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
J Gen Virol ; 99(8): 1044-1057, 2018 08.
Article em En | MEDLINE | ID: mdl-29916798
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Replicação Viral / Proteínas não Estruturais Virais / Substituição de Aminoácidos / Vírus da Dengue Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Replicação Viral / Proteínas não Estruturais Virais / Substituição de Aminoácidos / Vírus da Dengue Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão