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Urate mitigates oxidative stress and motor neuron toxicity of astrocytes derived from ALS-linked SOD1G93A mutant mice.
Bakshi, Rachit; Xu, Yuehang; Mueller, Kaly A; Chen, Xiqun; Granucci, Eric; Paganoni, Sabrina; Sadri-Vakili, Ghazaleh; Schwarzschild, Michael A.
Afiliação
  • Bakshi R; Molecular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, MA, USA. Electronic address: rbakshi1@mgh.harvard.edu.
  • Xu Y; Molecular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, MA, USA.
  • Mueller KA; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, MA, USA.
  • Chen X; Molecular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, MA, USA.
  • Granucci E; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, MA, USA.
  • Paganoni S; Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Department of PM&R, Spaulding Rehabilitation Hospital, USA.
  • Sadri-Vakili G; NeuroEpigenetics Laboratory, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, MA, USA.
  • Schwarzschild MA; Molecular Neurobiology Laboratory, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Boston, MA, USA.
Mol Cell Neurosci ; 92: 12-16, 2018 10.
Article em En | MEDLINE | ID: mdl-29928993

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Úrico / Astrócitos / Estresse Oxidativo / Superóxido Dismutase-1 / Esclerose Lateral Amiotrófica / Neurônios Motores / Antioxidantes Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Úrico / Astrócitos / Estresse Oxidativo / Superóxido Dismutase-1 / Esclerose Lateral Amiotrófica / Neurônios Motores / Antioxidantes Idioma: En Ano de publicação: 2018 Tipo de documento: Article