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Kub5-Hera RPRD1B Deficiency Promotes "BRCAness" and Vulnerability to PARP Inhibition in BRCA-proficient Breast Cancers.
Motea, Edward A; Fattah, Farjana J; Xiao, Ling; Girard, Luc; Rommel, Amy; Morales, Julio C; Patidar, Praveen; Zhou, Yunyun; Porter, Andrew; Xie, Yang; Minna, John D; Boothman, David A.
Afiliação
  • Motea EA; Departments of Pharmacology and Radiation Oncology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas. dboothm@iu.edu eamotea@iu.edu.
  • Fattah FJ; Departments of Pharmacology and Radiation Oncology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Xiao L; Departments of Pharmacology and Radiation Oncology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Girard L; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Rommel A; Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California.
  • Morales JC; Department of Neurosurgery, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma.
  • Patidar P; Department of Chemistry, New Mexico Institute of Mining and Technology, Socorro, New Mexico.
  • Zhou Y; Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Porter A; Center for Hematology, Imperial College, London, United Kingdom.
  • Xie Y; Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Minna JD; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Boothman DA; Departments of Pharmacology and Radiation Oncology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas. dboothm@iu.edu eamotea@iu.edu.
Clin Cancer Res ; 24(24): 6459-6470, 2018 12 15.
Article em En | MEDLINE | ID: mdl-30108102
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Poli(ADP-Ribose) Polimerases / Proteínas de Ciclo Celular / Genes BRCA1 / Genes BRCA2 / Proteínas de Neoplasias Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Poli(ADP-Ribose) Polimerases / Proteínas de Ciclo Celular / Genes BRCA1 / Genes BRCA2 / Proteínas de Neoplasias Idioma: En Ano de publicação: 2018 Tipo de documento: Article