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Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.
Fujimori, Koki; Ishikawa, Mitsuru; Otomo, Asako; Atsuta, Naoki; Nakamura, Ryoichi; Akiyama, Tetsuya; Hadano, Shinji; Aoki, Masashi; Saya, Hideyuki; Sobue, Gen; Okano, Hideyuki.
Afiliação
  • Fujimori K; Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Ishikawa M; Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
  • Otomo A; The Institute of Medical Sciences, Tokai University, Isehara, Kanagawa, Japan.
  • Atsuta N; Department of Molecular Life Sciences, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  • Nakamura R; Micro/Nano Technology Center, Tokai University, Hiratsuka, Kanagawa, Japan.
  • Akiyama T; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Hadano S; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Aoki M; Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
  • Saya H; The Institute of Medical Sciences, Tokai University, Isehara, Kanagawa, Japan.
  • Sobue G; Department of Molecular Life Sciences, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  • Okano H; Research Center for Brain and Nervous Diseases, Tokai University Graduate School of Medicine, Isehara, Kanagawa, Japan.
Nat Med ; 24(10): 1579-1589, 2018 10.
Article em En | MEDLINE | ID: mdl-30127392
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Agregação Patológica de Proteínas / Esclerose Lateral Amiotrófica / Neurônios Motores / Degeneração Neural Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Agregação Patológica de Proteínas / Esclerose Lateral Amiotrófica / Neurônios Motores / Degeneração Neural Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão