PPARÎ³ provides anti-inflammatory and protective effects in intrahepatic cholestasis of pregnancy through NF-&#954;B pathway.

Zhang, Yan; Huang, Xiaoping; Zhou, Jie; Yin, Yongxiang; Zhang, Ting; Chen, Daozhen

PPARÎ³ provides anti-inflammatory and protective effects in intrahepatic cholestasis of pregnancy through NF-κB pathway.

Zhang, Yan; Huang, Xiaoping; Zhou, Jie; Yin, Yongxiang; Zhang, Ting; Chen, Daozhen.

Afiliação

Zhang Y; Department of Gynecology and Obstetrics, Wuxi Maternal and Child Health Hospital, The Affiliated Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214002, China. Electronic address: yaoxue2030@163.com.
Huang X; Department of Gynecology and Obstetrics, Wuxi Maternal and Child Health Hospital, The Affiliated Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214002, China.
Zhou J; Department of Gynecology and Obstetrics, Wuxi Maternal and Child Health Hospital, The Affiliated Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214002, China.
Yin Y; Department of Gynecology and Obstetrics, Wuxi Maternal and Child Health Hospital, The Affiliated Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214002, China.
Zhang T; Department of Gynecology and Obstetrics, Wuxi Maternal and Child Health Hospital, The Affiliated Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214002, China.
Chen D; Department of Gynecology and Obstetrics, Wuxi Maternal and Child Health Hospital, The Affiliated Hospital of Nanjing Medical University, Wuxi, Jiangsu, 214002, China. Electronic address: chendaozhen@163.com.

Biochem Biophys Res Commun ; 504(4): 834-842, 2018 10 12.

Article em En | MEDLINE | ID: mdl-30219229

Assuntos

Colestase Intra-Hepática/metabolismo; NF-kappa B/metabolismo; PPAR gama/metabolismo; Complicações na Gravidez/metabolismo; Adulto; Animais; Linhagem Celular; Citocinas/sangue; Modelos Animais de Doenças; Feminino; Humanos; Inflamação/metabolismo; Redes e Vias Metabólicas; PPAR gama/genética; Placenta/metabolismo; Gravidez; Ratos; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Inflammation; Intrahepatic cholestasis of pregnancy; NF-κB; Oxidative stress; PPARÎ³

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complicações na Gravidez / Colestase Intra-Hepática / NF-kappa B / PPAR gama Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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