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Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects.
Rizzi, Elen; Amaral, Jefferson H; Guimarães, Danielle A; Conde-Tella, Sandra O; Pinheiro, Lucas C; Gerlach, Raquel F; Castro, Michele M; Tanus-Santos, Jose E.
Afiliação
  • Rizzi E; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil; Biotechnology Unit, Ribeirao Preto University, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil.
  • Amaral JH; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil.
  • Guimarães DA; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil.
  • Conde-Tella SO; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil.
  • Pinheiro LC; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil.
  • Gerlach RF; Department of Morphology, Estomatology and Physiology, Dental School of Ribeirao Preto, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil.
  • Castro MM; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil.
  • Tanus-Santos JE; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Av. Bandeirantes, 3900, Ribeirao Preto, SP 14049-900, Brazil. Electronic address: tanus@fmrp.usp.br.
Free Radic Biol Med ; 130: 234-243, 2019 01.
Article em En | MEDLINE | ID: mdl-30399409
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Metaloproteinase 2 da Matriz / Hipertensão Renovascular / Nitritos Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Metaloproteinase 2 da Matriz / Hipertensão Renovascular / Nitritos Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil