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The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity.
Becker, Jordan R; Cuella-Martin, Raquel; Barazas, Marco; Liu, Rui; Oliveira, Catarina; Oliver, Antony W; Bilham, Kirstin; Holt, Abbey B; Blackford, Andrew N; Heierhorst, Jörg; Jonkers, Jos; Rottenberg, Sven; Chapman, J Ross.
Afiliação
  • Becker JR; Genome Integrity Laboratory, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Cuella-Martin R; Genome Integrity Laboratory, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Barazas M; Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Liu R; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia.
  • Oliveira C; Genome Integrity Laboratory, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Oliver AW; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, BN1 9RQ, UK.
  • Bilham K; Genome Integrity Laboratory, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Holt AB; MRC Brain Network Dynamics Unit, Department of Pharmacology, University of Oxford, Oxford, OX1 3TH, UK.
  • Blackford AN; Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Heierhorst J; CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, OX3 7DQ, UK.
  • Jonkers J; St. Vincent's Institute of Medical Research, Fitzroy, VIC, 3065, Australia.
  • Rottenberg S; Department of Medicine at St. Vincent's Hospital, Melbourne Medical School, The University of Melbourne, Fitzroy, VIC, 3065, Australia.
  • Chapman JR; Division of Molecular Pathology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
Nat Commun ; 9(1): 5406, 2018 12 17.
Article em En | MEDLINE | ID: mdl-30559443
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteína BRCA1 / Dineínas do Citoplasma / Reparo do DNA por Junção de Extremidades / Inibidores de Poli(ADP-Ribose) Polimerases / Proteína 1 de Ligação à Proteína Supressora de Tumor p53 Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteína BRCA1 / Dineínas do Citoplasma / Reparo do DNA por Junção de Extremidades / Inibidores de Poli(ADP-Ribose) Polimerases / Proteína 1 de Ligação à Proteína Supressora de Tumor p53 Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido