Tackling Cancer with Yeast-Based Technologies.
Trends Biotechnol
; 37(6): 592-603, 2019 06.
Article
em En
| MEDLINE
| ID: mdl-30583804
ABSTRACT
The ability to precisely engineer yeast, coupled with its genetic and metabolic similarity to tumor cells, has enabled researchers to use this organism in cancer research. Here we review advances that leveraged yeast as a model organism for studying cancer biology, including the investigation of tumorigenic mechanisms, development of advanced technologies for drug discovery, production of anticancer drugs on an industrial scale, and delivering the next generation of immunotherapies.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Saccharomyces cerevisiae
/
Bioengenharia
/
Modelos Biológicos
/
Neoplasias
/
Antineoplásicos
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Suécia