Specific refolding pathway of viscumin A chain in membrane-like medium reveals a possible mechanism of toxin entry into cell.

Volynsky, Pavel E; Nolde, Dmitry E; Zakharova, Galina S; Palmer, Rex A; Tonevitsky, Alexander G; Efremov, Roman G

Volynsky, Pavel E; Nolde, Dmitry E; Zakharova, Galina S; Palmer, Rex A; Tonevitsky, Alexander G; Efremov, Roman G.

Afiliação

Volynsky PE; M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Street, 16/10, Moscow, 117997, Russia.
Nolde DE; M.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Street, 16/10, Moscow, 117997, Russia.
Zakharova GS; Scientific and Research Center "BioClinicum", Ugreshkaya Street, 2/85, Moscow, 115088, Russia.
Palmer RA; Department of Crystallography, Biochemical Sciences, Birkbeck College, Malet St, London, WC1E7HX, UK.
Tonevitsky AG; Scientific and Research Center "BioClinicum", Ugreshkaya Street, 2/85, Moscow, 115088, Russia.
Efremov RG; National Research University Higher School of Economics, Myasnitskaya ul. 20, 101000, Moscow, Russia.

Sci Rep ; 9(1): 413, 2019 01 23.

Article em En | MEDLINE | ID: mdl-30674891

Assuntos

Membrana Celular/química; Membranas Artificiais; Redobramento de Proteína; Proteínas Inativadoras de Ribossomos Tipo 2/química; Toxinas Biológicas/química; Transporte Proteico

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxinas Biológicas / Membrana Celular / Proteínas Inativadoras de Ribossomos Tipo 2 / Redobramento de Proteína / Membranas Artificiais Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Federação Russa

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