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Single-Cell Proteomics Reveal that Quantitative Changes in Co-expressed Lineage-Specific Transcription Factors Determine Cell Fate.
Palii, Carmen G; Cheng, Qian; Gillespie, Mark A; Shannon, Paul; Mazurczyk, Michalina; Napolitani, Giorgio; Price, Nathan D; Ranish, Jeffrey A; Morrissey, Edward; Higgs, Douglas R; Brand, Marjorie.
Afiliação
  • Palii CG; Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada; Department of Medicine, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H8L6, Canada.
  • Cheng Q; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
  • Gillespie MA; Institute for Systems Biology, Seattle, WA 98109, USA.
  • Shannon P; Institute for Systems Biology, Seattle, WA 98109, USA.
  • Mazurczyk M; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
  • Napolitani G; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.
  • Price ND; Institute for Systems Biology, Seattle, WA 98109, USA.
  • Ranish JA; Institute for Systems Biology, Seattle, WA 98109, USA.
  • Morrissey E; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK. Electronic address: edward.morrissey@imm.ox.ac.uk.
  • Higgs DR; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK. Electronic address: doug.higgs@imm.ox.ac.uk.
  • Brand M; Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, ON K1H8L6, Canada; Department of Medicine, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H8L6, Canada. Electronic address: mbrand@ohri.ca.
Cell Stem Cell ; 24(5): 812-820.e5, 2019 05 02.
Article em En | MEDLINE | ID: mdl-30880026

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Proteômica / Eritropoese Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Proteômica / Eritropoese Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá