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Copper sulfide: An emerging adaptable nanoplatform in cancer theranostics.
Poudel, Kishwor; Gautam, Milan; Jin, Sung Giu; Choi, Han-Gon; Yong, Chul Soon; Kim, Jong Oh.
Afiliação
  • Poudel K; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, Republic of Korea.
  • Gautam M; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, Republic of Korea.
  • Jin SG; Department of Pharmaceutical Engineering, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Republic of Korea.
  • Choi HG; College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan 15588, Republic of Korea.
  • Yong CS; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, Republic of Korea. Electronic address: csyong@ynu.ac.kr.
  • Kim JO; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan 712-749, Republic of Korea. Electronic address: jongohkim@yu.ac.kr.
Int J Pharm ; 562: 135-150, 2019 May 01.
Article em En | MEDLINE | ID: mdl-30904728
Copper sulfide nanoparticles (CuS NPs), emerging nanoplatforms with dual diagnostic and therapeutic applications, are being actively investigated in this era of "war on cancer" owing to their versatility and adaptability. This article discusses the pros and cons of using CuS NPs in diagnostics, therapeutics, and theranostics. The first section introduces CuS NPs and discusses the features that render them more advantageous than other established nanoplatforms in cancer management. Subsequent sections include specific in vitro and in vivo results of different studies showing the potential of CuS NPs as nanoplatforms. Methods used for visualization (photoacoustic imaging and magnetic resonance imaging) of CuS NPs and treatment (phototherapy and combinatorial therapy) have also been discussed. Furthermore, the challenges and opportunities associated with using CuS NPs have been elucidated. Further investigations on CuS NPs are required to translate it for clinical applications.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfetos / Cobre / Nanopartículas / Neoplasias Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfetos / Cobre / Nanopartículas / Neoplasias Idioma: En Ano de publicação: 2019 Tipo de documento: Article