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Boosting activity of high-fidelity CRISPR/Cas9 variants using a tRNAGln-processing system in human cells.
He, Xiubin; Wang, Yufei; Yang, Fayu; Wang, Bang; Xie, Haihua; Gu, Lingkai; Zhao, Tianyuan; Liu, Xiexie; Zhang, Dingbo; Ren, Qianwen; Liu, Xiaoyu; Liu, Yong; Gao, Caixia; Gu, Feng.
Afiliação
  • He X; From the School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Wang Y; the State Key Laboratory and Key Laboratory of Vision Science, Ministry of Health, Wenzhou, Zhejiang 325027, China.
  • Yang F; the Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry, Wenzhou, Zhejiang 325027, China.
  • Wang B; From the School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Xie H; the State Key Laboratory and Key Laboratory of Vision Science, Ministry of Health, Wenzhou, Zhejiang 325027, China.
  • Gu L; the Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry, Wenzhou, Zhejiang 325027, China.
  • Zhao T; From the School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Liu X; the State Key Laboratory and Key Laboratory of Vision Science, Ministry of Health, Wenzhou, Zhejiang 325027, China.
  • Zhang D; the Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry, Wenzhou, Zhejiang 325027, China.
  • Ren Q; From the School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Liu X; the State Key Laboratory and Key Laboratory of Vision Science, Ministry of Health, Wenzhou, Zhejiang 325027, China.
  • Liu Y; the Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry, Wenzhou, Zhejiang 325027, China.
  • Gao C; From the School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
  • Gu F; the State Key Laboratory and Key Laboratory of Vision Science, Ministry of Health, Wenzhou, Zhejiang 325027, China.
J Biol Chem ; 294(23): 9308-9315, 2019 06 07.
Article em En | MEDLINE | ID: mdl-31010827

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA de Transferência de Glutamina / Sistemas CRISPR-Cas / Edição de Genes Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA de Transferência de Glutamina / Sistemas CRISPR-Cas / Edição de Genes Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China