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Discovery of naphthacemycins as a novel class of PARP1 inhibitors.
Shen, Wenbin; Lu, Xinhua; Zhu, Jingtong; Mu, Yunlong; Xu, Yan; Gao, Jian; Zhang, Xuexia; Zheng, Zhihui.
Afiliação
  • Shen W; New Drug Research & Development Center, North China Pharmaceutical Group Corporation, Shijiazhuang 050015, Hebei, China; Key Laboratory for New Drug Screening Technology of Shijiazhuang City, Shijiazhuang 050015, Hebei, China.
  • Lu X; New Drug Research & Development Center, North China Pharmaceutical Group Corporation, Shijiazhuang 050015, Hebei, China; National Microbial Medicine Engineering & Research Center, Shijiazhuang 050015, Hebei, China; Key Laboratory for New Drug Screening Technology of Shijiazhuang City, Shijia
  • Zhu J; New Drug Research & Development Center, North China Pharmaceutical Group Corporation, Shijiazhuang 050015, Hebei, China; Key Laboratory for New Drug Screening Technology of Shijiazhuang City, Shijiazhuang 050015, Hebei, China.
  • Mu Y; National Microbial Medicine Engineering & Research Center, Shijiazhuang 050015, Hebei, China; Hebei Industry Microbial Metabolic Engineering & Technology Research Center, Shijiazhuang 050015, Hebei, China.
  • Xu Y; New Drug Research & Development Center, North China Pharmaceutical Group Corporation, Shijiazhuang 050015, Hebei, China; Hebei Industry Microbial Metabolic Engineering & Technology Research Center, Shijiazhuang 050015, Hebei, China.
  • Gao J; New Drug Research & Development Center, North China Pharmaceutical Group Corporation, Shijiazhuang 050015, Hebei, China; National Microbial Medicine Engineering & Research Center, Shijiazhuang 050015, Hebei, China.
  • Zhang X; New Drug Research & Development Center, North China Pharmaceutical Group Corporation, Shijiazhuang 050015, Hebei, China; National Microbial Medicine Engineering & Research Center, Shijiazhuang 050015, Hebei, China; Hebei Industry Microbial Metabolic Engineering & Technology Research Cent
  • Zheng Z; New Drug Research & Development Center, North China Pharmaceutical Group Corporation, Shijiazhuang 050015, Hebei, China; National Microbial Medicine Engineering & Research Center, Shijiazhuang 050015, Hebei, China; Key Laboratory for New Drug Screening Technology of Shijiazhuang City, Shijia
Bioorg Med Chem Lett ; 29(15): 1904-1908, 2019 08 01.
Article em En | MEDLINE | ID: mdl-31153806
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Descoberta de Drogas / Ensaios de Triagem em Larga Escala / Simulação de Acoplamento Molecular / Inibidores de Poli(ADP-Ribose) Polimerases / Naftacenos Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Descoberta de Drogas / Ensaios de Triagem em Larga Escala / Simulação de Acoplamento Molecular / Inibidores de Poli(ADP-Ribose) Polimerases / Naftacenos Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China