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Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia.
Kusakabe, Manabu; Sun, Ann Chong; Tyshchenko, Kateryna; Wong, Rachel; Nanda, Aastha; Shanna, Claire; Gusscott, Samuel; Chavez, Elizabeth A; Lorzadeh, Alireza; Zhu, Alice; Hill, Ainsleigh; Hung, Stacy; Brown, Scott; Babaian, Artem; Wang, Xuehai; Holt, Robert A; Steidl, Christian; Karsan, Aly; Humphries, R Keith; Eaves, Connie J; Hirst, Martin; Weng, Andrew P.
Afiliação
  • Kusakabe M; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Sun AC; Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, 305-8575, Japan.
  • Tyshchenko K; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Wong R; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Nanda A; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Shanna C; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Gusscott S; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Chavez EA; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Lorzadeh A; Lymphoid Cancer Research, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Zhu A; Department of Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, V6T 1Z4, BC, Canada.
  • Hill A; Department of Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, V6T 1Z4, BC, Canada.
  • Hung S; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Brown S; Lymphoid Cancer Research, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Babaian A; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Wang X; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Holt RA; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Steidl C; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Karsan A; Lymphoid Cancer Research, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Humphries RK; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Eaves CJ; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Hirst M; Terry Fox Laboratory, BC Cancer Agency, Vancouver, V5Z 1L3, BC, Canada.
  • Weng AP; Department of Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, V6T 1Z4, BC, Canada.
Nat Commun ; 10(1): 2913, 2019 07 02.
Article em En | MEDLINE | ID: mdl-31266935
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Família Multigênica / Proteínas de Homeodomínio Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Família Multigênica / Proteínas de Homeodomínio Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá