Your browser doesn't support javascript.
loading
Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation.
Indra, Radek; Pompach, Petr; Martínek, Václav; Takácsová, Paulína; Vavrová, Katarína; Heger, Zbynek; Adam, Vojtech; Eckschlager, Tomás; Kopecková, Katerina; Arlt, Volker Manfred; Stiborová, Marie.
Afiliação
  • Indra R; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, CZ-12843 Prague 2, Czech Republic.
  • Pompach P; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, CZ-12843 Prague 2, Czech Republic.
  • Martínek V; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, CZ-12843 Prague 2, Czech Republic.
  • Takácsová P; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, CZ-12843 Prague 2, Czech Republic.
  • Vavrová K; Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, CZ-12843 Prague 2, Czech Republic.
  • Heger Z; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-61300 Brno, Czech Republic.
  • Adam V; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-61300 Brno, Czech Republic.
  • Eckschlager T; Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, V Uvalu 84/1, CZ-150 06 Prague 5, Czech Republic.
  • Kopecková K; Department of Oncology, 2nd Medical Faculty, Charles University and University Hospital Motol, V Uvalu 84/1, CZ-150 06 Prague 5, Czech Republic.
  • Arlt VM; Department of Analytical, Environmental and Forensic Sciences, MRC-PHE Centre for Environment and Health, King's College London, 150 Stamford Street, London SE1 9NH, UK.
  • Stiborová M; NIHR Health Protection Research Unit in Health Impact of Environmental Hazards at King's College London in partnership with Public Health England and Imperial College London, 150 Stamford Street, London SE1 9NH, UK.
Int J Mol Sci ; 20(14)2019 Jul 10.
Article em En | MEDLINE | ID: mdl-31295928
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredução / Piperidinas / Quinazolinas / Inibidores de Proteínas Quinases / Enzimas / Citocromo P-450 CYP3A / Antineoplásicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: República Tcheca
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredução / Piperidinas / Quinazolinas / Inibidores de Proteínas Quinases / Enzimas / Citocromo P-450 CYP3A / Antineoplásicos Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: República Tcheca