Gel Phase 1,2-Distearoyl-<i>sn</i>-glycero-3-phosphocholine-Based Liposomes Are Superior to Fluid Phase Liposomes at Augmenting Both Antigen Presentation on Major Histocompatibility Complex Class II and Costimulatory Molecule Display by Dendritic Cells <i>in Vitro</i>.

Norling, Karin; Bernasconi, Valentina; Agmo Hernández, Víctor; Parveen, Nagma; Edwards, Katarina; Lycke, Nils Y; Höök, Fredrik; Bally, Marta

Gel Phase 1,2-Distearoyl-sn-glycero-3-phosphocholine-Based Liposomes Are Superior to Fluid Phase Liposomes at Augmenting Both Antigen Presentation on Major Histocompatibility Complex Class II and Costimulatory Molecule Display by Dendritic Cells in Vitro.

Norling, Karin; Bernasconi, Valentina; Agmo Hernández, Víctor; Parveen, Nagma; Edwards, Katarina; Lycke, Nils Y; Höök, Fredrik; Bally, Marta.

Afiliação

Norling K; Division of Biological Physics, Department of Physics , Chalmers University of Technology , 412 96 Gothenburg , Sweden.
Bernasconi V; Mucosal Immunobiology and Vaccine Center (MIVAC), Department of Microbiology and Immunology, Institute of Biomedicine , University of Gothenburg , 405 30 Gothenburg , Sweden.
Agmo Hernández V; Department of Chemistry, BMC , Uppsala University , Box 599, 752 37 Uppsala , Sweden.
Parveen N; Department of Pharmacy , Uppsala University , Box 580, 751 23 , Uppsala , Sweden.
Edwards K; Division of Biological Physics, Department of Physics , Chalmers University of Technology , 412 96 Gothenburg , Sweden.
Lycke NY; Department of Chemistry, BMC , Uppsala University , Box 599, 752 37 Uppsala , Sweden.
Höök F; Mucosal Immunobiology and Vaccine Center (MIVAC), Department of Microbiology and Immunology, Institute of Biomedicine , University of Gothenburg , 405 30 Gothenburg , Sweden.
Bally M; Division of Biological Physics, Department of Physics , Chalmers University of Technology , 412 96 Gothenburg , Sweden.

ACS Infect Dis ; 5(11): 1867-1878, 2019 11 08.

Article em En | MEDLINE | ID: mdl-31498993

Assuntos

Células Dendríticas/imunologia; Antígenos de Histocompatibilidade Classe II/imunologia; Lipossomos/imunologia; Fosfatidilcolinas/química; Adjuvantes Imunológicos/química; Adjuvantes Imunológicos/farmacologia; Animais; Apresentação de Antígeno; Antígeno B7-1/imunologia; Células Cultivadas; Citocinas/imunologia; Portadores de Fármacos/química; Portadores de Fármacos/farmacologia; Feminino; Lipossomos/química; Camundongos; Camundongos Endogâmicos C57BL; Fosfatidilcolinas/imunologia; Vacinas/química; Vacinas/farmacologia

Palavras-chave

adjuvant effect; antigen delivery; dendritic cell activation; immunogenicity; lipid nanoparticle; mucosal vaccination

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatidilcolinas / Células Dendríticas / Antígenos de Histocompatibilidade Classe II / Lipossomos Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suécia

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