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The double inhibition of PDK1 and STAT3-Y705 prevents liver metastasis in colorectal cancer.
Qin, Wenjuan; Tian, Yun; Zhang, Jing; Liu, Wenjian; Zhou, Qiming; Hu, Sheng; Yang, Fei; Lu, Li; Lu, Haijie; Cui, Shuzhong; Wen, Lu; Wei, Shaozhong.
Afiliação
  • Qin W; Department of Radiation Oncology, Zhongshan Hospital Affiliated by Xiamen University, Xiamen, Fujian, China.
  • Tian Y; Department of Abdominal Surgery, The Cancer Hospital Affiliated by Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Zhang J; Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Liu W; Department of Hematological Oncology, Sun Yat-Sen Cancer Center, Guangzhou, Guangdong, China.
  • Zhou Q; Department of Oncology, The Sixth People's Hospital, Shenzhen, Guangdong, China.
  • Hu S; Department of Medical Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Yang F; Department of Pathology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Lu L; Department of Gastrointestinal Surgery & Colorectal Cancer Center of Hubei Province, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Lu H; Department of Radiation Oncology, Zhongshan Hospital Affiliated by Xiamen University, Xiamen, Fujian, China.
  • Cui S; Department of Abdominal Surgery, The Cancer Hospital Affiliated by Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Wen L; Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. wenlu2808@126.com.
  • Wei S; Department of Gastrointestinal Surgery & Colorectal Cancer Center of Hubei Province, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. weishaozhong1@163.com.
Sci Rep ; 9(1): 12973, 2019 09 10.
Article em En | MEDLINE | ID: mdl-31506552
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenantrenos / Neoplasias Colorretais / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Fator de Transcrição STAT3 / Piruvato Desidrogenase Quinase de Transferência de Acetil / Neoplasias Hepáticas Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenantrenos / Neoplasias Colorretais / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Fator de Transcrição STAT3 / Piruvato Desidrogenase Quinase de Transferência de Acetil / Neoplasias Hepáticas Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China