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Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system.
Zelaszczyk, Dorota; Jakubczyk, Magdalena; Pytka, Karolina; Rapacz, Anna; Walczak, Maria; Janiszewska, Paulina; Panczyk, Katarzyna; Zmudzki, Pawel; Sloczynska, Karolina; Marona, Henryk; Waszkielewicz, Anna M.
Afiliação
  • Zelaszczyk D; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Bioorganic Chemistry, Chair of Organic Chemistry, Poland. Electronic address: dorota.zelaszczyk@uj.edu.pl.
  • Jakubczyk M; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Pharmacodynamics, Poland.
  • Pytka K; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Pharmacodynamics, Poland.
  • Rapacz A; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Pharmacodynamics, Poland.
  • Walczak M; Jagiellonian University Medical College, Faculty of Pharmacy, Chair and Department of Toxicology, Poland.
  • Janiszewska P; Jagiellonian University Medical College, Faculty of Pharmacy, Chair and Department of Toxicology, Poland.
  • Panczyk K; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Bioorganic Chemistry, Chair of Organic Chemistry, Poland.
  • Zmudzki P; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Poland.
  • Sloczynska K; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Pharmaceutical Biochemistry, Poland.
  • Marona H; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Bioorganic Chemistry, Chair of Organic Chemistry, Poland.
  • Waszkielewicz AM; Jagiellonian University Medical College, Faculty of Pharmacy, Department of Bioorganic Chemistry, Chair of Organic Chemistry, Poland.
Bioorg Med Chem Lett ; 29(21): 126679, 2019 11 01.
Article em En | MEDLINE | ID: mdl-31537425
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Ansiolíticos / Sistema Nervoso Central / Xantonas / Antidepressivos Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Ansiolíticos / Sistema Nervoso Central / Xantonas / Antidepressivos Idioma: En Ano de publicação: 2019 Tipo de documento: Article