LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses.

Xu, Huan; Xu, Xiuduan; Wang, Hongli; Qimuge, Aodeng; Liu, Shasha; Chen, Yuanlian; Zhang, Chongchong; Hu, Meiru; Song, Lun

Xu, Huan; Xu, Xiuduan; Wang, Hongli; Qimuge, Aodeng; Liu, Shasha; Chen, Yuanlian; Zhang, Chongchong; Hu, Meiru; Song, Lun.

Afiliação

Xu H; Institute of Military Cognitive and Brain Sciences, 27 Taiping Road, Beijing, 100850, People's Republic of China.
Xu X; Anhui Medical University, 81 Meishan Road, Hefei, 230032, People's Republic of China.
Wang H; Institute of Military Cognitive and Brain Sciences, 27 Taiping Road, Beijing, 100850, People's Republic of China.
Qimuge A; Anhui Medical University, 81 Meishan Road, Hefei, 230032, People's Republic of China.
Liu S; School of Life Sciences, Tsinghua University, Beijing, China.
Chen Y; Institute of Military Cognitive and Brain Sciences, 27 Taiping Road, Beijing, 100850, People's Republic of China.
Zhang C; Laboratory of Cellular and Molecular Immunology, School of Medicine, Henan University, 357 Ximen Road, Kaifeng, 475004, People's Republic of China.
Hu M; Institute of Military Cognitive and Brain Sciences, 27 Taiping Road, Beijing, 100850, People's Republic of China.
Song L; Department of New Drug Screening Center, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China.

Sci Rep ; 9(1): 16600, 2019 11 12.

Article em En | MEDLINE | ID: mdl-31719630

Assuntos

Proteínas Reguladoras de Apoptose/metabolismo; Autofagia; Material Particulado/efeitos adversos; Monoéster Fosfórico Hidrolases/metabolismo; Pneumonia/etiologia; Proteínas Serina-Treonina Quinases/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Fator A de Crescimento do Endotélio Vascular/metabolismo; Quinases Proteína-Quinases Ativadas por AMP; Animais; Proteínas Reguladoras de Apoptose/genética; Células Cultivadas; Humanos; Monoéster Fosfórico Hidrolases/genética; Pneumonia/metabolismo; Pneumonia/patologia; Proteínas Serina-Treonina Quinases/genética; Ratos; Ratos Sprague-Dawley; Transdução de Sinais; Proteína Supressora de Tumor p53/genética; Fator A de Crescimento do Endotélio Vascular/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia / Autofagia / Proteína Supressora de Tumor p53 / Proteínas Serina-Treonina Quinases / Monoéster Fosfórico Hidrolases / Fator A de Crescimento do Endotélio Vascular / Proteínas Reguladoras de Apoptose / Material Particulado Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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