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Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia.
Choumessi, Aphrodite T; Johanns, Manuel; Beaufay, Claire; Herent, Marie-France; Stroobant, Vincent; Vertommen, Didier; Corbet, Cyril; Jacobs, Roxane; Herinckx, Gaëtan; Steinberg, Gregory R; Feron, Olivier; Quetin-Leclercq, Joëlle; Rider, Mark H.
Afiliação
  • Choumessi AT; Université catholique de Louvain (UCLouvain) and de Duve Institute (DDUV), Avenue Hippocrate 75, 1200 Brussels, Belgium.
  • Johanns M; Université catholique de Louvain (UCLouvain) and de Duve Institute (DDUV), Avenue Hippocrate 75, 1200 Brussels, Belgium.
  • Beaufay C; Université catholique de Louvain (UCLouvain) and Louvain Drug Research Institute (LDRI), Avenue Mounier 73, 1200 Brussels, Belgium.
  • Herent MF; Université catholique de Louvain (UCLouvain) and Louvain Drug Research Institute (LDRI), Avenue Mounier 73, 1200 Brussels, Belgium.
  • Stroobant V; Ludwig Institute for Cancer Research, Avenue Hippocrate 75, 1200 Brussels, Belgium.
  • Vertommen D; Université catholique de Louvain (UCLouvain) and de Duve Institute (DDUV), Avenue Hippocrate 75, 1200 Brussels, Belgium.
  • Corbet C; Université catholique de Louvain (UCLouvain) and Institute of Experimental and Clinical Research (IREC), Avenue Hippocrate 57, 1200 Brussels, Belgium.
  • Jacobs R; Université catholique de Louvain (UCLouvain) and de Duve Institute (DDUV), Avenue Hippocrate 75, 1200 Brussels, Belgium.
  • Herinckx G; Université catholique de Louvain (UCLouvain) and de Duve Institute (DDUV), Avenue Hippocrate 75, 1200 Brussels, Belgium.
  • Steinberg GR; Department of Medicine, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada.
  • Feron O; Department of Biochemistry and Sciences, Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada.
  • Quetin-Leclercq J; Université catholique de Louvain (UCLouvain) and Institute of Experimental and Clinical Research (IREC), Avenue Hippocrate 57, 1200 Brussels, Belgium.
  • Rider MH; Université catholique de Louvain (UCLouvain) and Louvain Drug Research Institute (LDRI), Avenue Mounier 73, 1200 Brussels, Belgium.
Biochem J ; 476(24): 3687-3704, 2019 12 19.
Article em En | MEDLINE | ID: mdl-31782497
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flavonoides / Glicemia / Moraceae / Gluconeogênese / Glucose Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flavonoides / Glicemia / Moraceae / Gluconeogênese / Glucose Idioma: En Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica