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T618I CSF3R mutations in chronic neutrophilic leukemia induce oncogenic signals through aberrant trafficking and constitutive phosphorylation of the O-glycosylated receptor form.
Price, Andrea; Druhan, Lawrence J; Lance, Amanda; Clark, Gavin; Vestal, C Greer; Zhang, Qing; Foureau, David; Parsons, Judy; Hamilton, Alicia; Steuerwald, Nury M; Avalos, Belinda R.
Afiliação
  • Price A; Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Druhan LJ; Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Lance A; Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Clark G; Cornell University, Ithaca, NY, USA.
  • Vestal CG; Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Zhang Q; Department of Cancer Biostatistics, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Foureau D; Immune Monitoring Core Laboratory, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Parsons J; Molecular Biology and Genomics Laboratory, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Hamilton A; Molecular Biology and Genomics Laboratory, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Steuerwald NM; Molecular Biology and Genomics Laboratory, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
  • Avalos BR; Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA. Electronic address: belinda.avalos@atriumhealth.org.
Biochem Biophys Res Commun ; 523(1): 208-213, 2020 02 26.
Article em En | MEDLINE | ID: mdl-31848046
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oncogenes / Leucemia Neutrofílica Crônica / Transdução de Sinais / Receptores de Fator Estimulador de Colônias Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oncogenes / Leucemia Neutrofílica Crônica / Transdução de Sinais / Receptores de Fator Estimulador de Colônias Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos