An atypical keloid in a Brazilian man.
Med Sante Trop
; 29(4): 377-380, 2019 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-31884985
ABSTRACT
Case report from French Guiana of an atypical keloid in a Brazilian man Lobomycosis. Lobomycosis is a rare fungal skin infection, endemic to the Amazon basin. Its clinical manifestations are slow-growing keloid-like nodules, with a granulomatous reaction on histopathology. The etiological agent, Lacazia loboi, has never been isolated in the environment or cultured in a laboratory. Diagnosis is based on the typical appearance on microscopy. Treatment is disappointing, with a high recurrence rate. We report a new case in French Guiana and review the literature. Only 10 cases have been reported outside of the endemic area, 2 involving no travel; the mean time to diagnosis was 21 years. Phylogenetic analysis has recently proved that lobomycosis in dolphins is caused by a fungus more closely related to Paracoccidioides brasiliensis than to L. loboi (two very closely related species). Molecular diagnosis is possible in a few centers. Climate change may result in spreading lobomycosis to currently disease-free areas of the world.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Lacazia
/
Lobomicose
País/Região como assunto:
America do sul
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Brasil
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Guyana francesa
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article