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Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B.
Grover, Anita; Crippen-Harmon, Danielle; Nave, Lacey; Vincelette, Jon; Wait, Jill C M; Melton, Andrew C; Lawrence, Roger; Brown, Jillian R; Webster, Katherine A; Yip, Bryan K; Baridon, Brian; Vitelli, Catherine; Rigney, Sara; Christianson, Terri M; Tiger, Pascale M N; Lo, Melanie J; Holtzinger, John; Shaywitz, Adam J; Crawford, Brett E; Fitzpatrick, Paul A; LeBowitz, Jonathan H; Bullens, Sherry; Aoyagi-Scharber, Mika; Bunting, Stuart; O'Neill, Charles A; Pinkstaff, Jason; Bagri, Anil.
Afiliação
  • Grover A; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Crippen-Harmon D; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Nave L; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Vincelette J; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Wait JCM; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Melton AC; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Lawrence R; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Brown JR; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Webster KA; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Yip BK; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Baridon B; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Vitelli C; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Rigney S; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Christianson TM; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Tiger PMN; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Lo MJ; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Holtzinger J; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Shaywitz AJ; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Crawford BE; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Fitzpatrick PA; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • LeBowitz JH; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Bullens S; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Aoyagi-Scharber M; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Bunting S; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • O'Neill CA; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA. coneill@bmrn.com.
  • Pinkstaff J; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
  • Bagri A; BioMarin Pharmaceutical Inc., 105 Digital Drive, Novato, CA, 94949, USA.
Drug Deliv Transl Res ; 10(2): 425-439, 2020 04.
Article em En | MEDLINE | ID: mdl-31942701
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilglucosaminidase / Proteínas Recombinantes de Fusão / Fator de Crescimento Insulin-Like II / Barreira Hematoencefálica / Mucopolissacaridose III / Receptor IGF Tipo 2 Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilglucosaminidase / Proteínas Recombinantes de Fusão / Fator de Crescimento Insulin-Like II / Barreira Hematoencefálica / Mucopolissacaridose III / Receptor IGF Tipo 2 Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos