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The PI3K subunits, P110α and P110ß are potential targets for overcoming P-gp and BCRP-mediated MDR in cancer.
Zhang, Lei; Li, Yidong; Wang, Qianchao; Chen, Zhuo; Li, Xiaoyun; Wu, Zhuoxun; Hu, Chaohua; Liao, Dan; Zhang, Wei; Chen, Zhe-Sheng.
Afiliação
  • Zhang L; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
  • Li Y; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA.
  • Wang Q; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA.
  • Chen Z; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
  • Li X; State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China. zchen@fjirsm.ac.cn.
  • Wu Z; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA.
  • Hu C; College of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, Guangdong, China.
  • Liao D; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA.
  • Zhang W; College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
  • Chen ZS; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA.
Mol Cancer ; 19(1): 10, 2020 01 17.
Article em En | MEDLINE | ID: mdl-31952518
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Resistência a Múltiplos Medicamentos / Inibidores de Proteínas Quinases / Classe I de Fosfatidilinositol 3-Quinases / Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP / Proteínas de Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Resistência a Múltiplos Medicamentos / Inibidores de Proteínas Quinases / Classe I de Fosfatidilinositol 3-Quinases / Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP / Proteínas de Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China