Toll-Like Receptor 5 Signaling Ameliorates Liver Fibrosis by Inducing Interferon ß-Modulated IL-1 Receptor Antagonist in Mice.

Zhou, Zixiong; Kim, Jong-Won; Qi, Jing; Eo, Seong Kug; Lim, Chae Woong; Kim, Bumseok

Zhou, Zixiong; Kim, Jong-Won; Qi, Jing; Eo, Seong Kug; Lim, Chae Woong; Kim, Bumseok.

Afiliação

Zhou Z; Biosafety Research Institute, and the BK21 Plus Program, College of Veterinary Medicine, Jeonbuk National University, Iksan, Jeonbuk, South Korea.
Kim JW; Biosafety Research Institute, and the BK21 Plus Program, College of Veterinary Medicine, Jeonbuk National University, Iksan, Jeonbuk, South Korea.
Qi J; Biosafety Research Institute, and the BK21 Plus Program, College of Veterinary Medicine, Jeonbuk National University, Iksan, Jeonbuk, South Korea.
Eo SK; Biosafety Research Institute, and the BK21 Plus Program, College of Veterinary Medicine, Jeonbuk National University, Iksan, Jeonbuk, South Korea.
Lim CW; Biosafety Research Institute, and the BK21 Plus Program, College of Veterinary Medicine, Jeonbuk National University, Iksan, Jeonbuk, South Korea.
Kim B; Biosafety Research Institute, and the BK21 Plus Program, College of Veterinary Medicine, Jeonbuk National University, Iksan, Jeonbuk, South Korea. Electronic address: bskims@jbnu.ac.kr.

Am J Pathol ; 190(3): 614-629, 2020 03.

Article em En | MEDLINE | ID: mdl-31972159

Assuntos

Colestase/complicações; Interferon beta/metabolismo; Proteína Antagonista do Receptor de Interleucina 1/metabolismo; Cirrose Hepática/fisiopatologia; Transdução de Sinais; Receptor 5 Toll-Like/metabolismo; Imunidade Adaptativa; Animais; Modelos Animais de Doenças; Progressão da Doença; Flagelina/administração & dosagem; Imunidade Inata; Interferon beta/genética; Proteína Antagonista do Receptor de Interleucina 1/genética; Cirrose Hepática/induzido quimicamente; Cirrose Hepática/etiologia; Cirrose Hepática/imunologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Receptor de Interferon alfa e beta/genética; Receptor 5 Toll-Like/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Colestase / Interferon beta / Receptor 5 Toll-Like / Proteína Antagonista do Receptor de Interleucina 1 / Cirrose Hepática Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Coréia do Sul

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