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Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.
Zhao, Steven; Jang, Cholsoon; Liu, Joyce; Uehara, Kahealani; Gilbert, Michael; Izzo, Luke; Zeng, Xianfeng; Trefely, Sophie; Fernandez, Sully; Carrer, Alessandro; Miller, Katelyn D; Schug, Zachary T; Snyder, Nathaniel W; Gade, Terence P; Titchenell, Paul M; Rabinowitz, Joshua D; Wellen, Kathryn E.
Afiliação
  • Zhao S; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Jang C; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Liu J; Cell & Molecular Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Uehara K; Department of Chemistry and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
  • Gilbert M; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Izzo L; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Zeng X; Biochemistry & Molecular Biophysics Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Trefely S; Biochemistry & Molecular Biophysics Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Fernandez S; Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Carrer A; Institute of Diabetes, Obesity and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Miller KD; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Schug ZT; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Snyder NW; Biochemistry & Molecular Biophysics Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Gade TP; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Titchenell PM; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Rabinowitz JD; Cell & Molecular Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Wellen KE; Department of Chemistry and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
Nature ; 579(7800): 586-591, 2020 03.
Article em En | MEDLINE | ID: mdl-32214246
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lipogênese / Microbioma Gastrointestinal / Açúcares da Dieta / Frutose / Fígado / Acetatos Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lipogênese / Microbioma Gastrointestinal / Açúcares da Dieta / Frutose / Fígado / Acetatos Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos