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Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma.
Chung, Katherine Minjee; Singh, Jaffarguriqbal; Lawres, Lauren; Dorans, Kimberly Judith; Garcia, Cathy; Burkhardt, Daniel B; Robbins, Rebecca; Bhutkar, Arjun; Cardone, Rebecca; Zhao, Xiaojian; Babic, Ana; Vayrynen, Sara A; Dias Costa, Andressa; Nowak, Jonathan A; Chang, Daniel T; Dunne, Richard F; Hezel, Aram F; Koong, Albert C; Wilhelm, Joshua J; Bellin, Melena D; Nylander, Vibe; Gloyn, Anna L; McCarthy, Mark I; Kibbey, Richard G; Krishnaswamy, Smita; Wolpin, Brian M; Jacks, Tyler; Fuchs, Charles S; Muzumdar, Mandar Deepak.
Afiliação
  • Chung KM; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA.
  • Singh J; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA.
  • Lawres L; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA.
  • Dorans KJ; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA.
  • Garcia C; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA.
  • Burkhardt DB; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Robbins R; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA.
  • Bhutkar A; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA.
  • Cardone R; Departments of Internal Medicine and Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Zhao X; Departments of Internal Medicine and Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Babic A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02114, USA.
  • Vayrynen SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02114, USA.
  • Dias Costa A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02114, USA.
  • Nowak JA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Chang DT; Department of Radiation Oncology, Stanford Cancer Institute, Stanford, CA 94305, USA.
  • Dunne RF; Division of Hematology and Oncology, Department of Medicine, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14627, USA.
  • Hezel AF; Division of Hematology and Oncology, Department of Medicine, Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14627, USA.
  • Koong AC; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Wilhelm JJ; Schulze Diabetes Institute and Department of Surgery, University of Minnesota Medical Center, Minneapolis, MN 55454, USA.
  • Bellin MD; Schulze Diabetes Institute and Department of Surgery, University of Minnesota Medical Center, Minneapolis, MN 55454, USA; Department of Pediatrics, University of Minnesota Medical Center, Minneapolis, MN 55454, USA.
  • Nylander V; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.
  • Gloyn AL; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK; Oxford NIHR Biomedical Research Centre, Oxford Universi
  • McCarthy MI; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 7LE, UK; Oxford NIHR Biomedical Research Centre, Oxford Universi
  • Kibbey RG; Departments of Internal Medicine and Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Krishnaswamy S; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02114, USA.
  • Jacks T; Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Fuchs CS; Yale Cancer Center, Smilow Cancer Hospital, New Haven, CT 06511, USA.
  • Muzumdar MD; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA; Yale Cancer Center, Smilow Cancer Hospital, New Haven, CT 06511, USA. Electronic address: mandar.muzumdar@yale.edu.
Cell ; 181(4): 832-847.e18, 2020 05 14.
Article em En | MEDLINE | ID: mdl-32304665

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Ductal Pancreático / Obesidade Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Ductal Pancreático / Obesidade Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos