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Dasatinib overcomes stroma-based resistance to the FLT3 inhibitor quizartinib using multiple mechanisms.
Patel, Ami B; Pomicter, Anthony D; Yan, Dongqing; Eiring, Anna M; Antelope, Orlando; Schumacher, Jonathan A; Kelley, Todd W; Tantravahi, Srinivas K; Kovacsovics, Tibor J; Shami, Paul J; O'Hare, Thomas; Deininger, Michael W.
Afiliação
  • Patel AB; Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, UT, USA.
  • Pomicter AD; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • Yan D; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • Eiring AM; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • Antelope O; Department of Molecular and Translational Medicine, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
  • Schumacher JA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • Kelley TW; ARUP Laboratories, Salt Lake City, UT, USA.
  • Tantravahi SK; Department of Pathology, University of Utah, Salt Lake City, UT, 84112, USA.
  • Kovacsovics TJ; Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, UT, USA.
  • Shami PJ; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
  • O'Hare T; Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, UT, USA.
  • Deininger MW; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Leukemia ; 34(11): 2981-2991, 2020 11.
Article em En | MEDLINE | ID: mdl-32409689
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Células Estromais / Resistencia a Medicamentos Antineoplásicos / Inibidores de Proteínas Quinases / Benzotiazóis / Tirosina Quinase 3 Semelhante a fms / Dasatinibe Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Células Estromais / Resistencia a Medicamentos Antineoplásicos / Inibidores de Proteínas Quinases / Benzotiazóis / Tirosina Quinase 3 Semelhante a fms / Dasatinibe Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos