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First-line pembrolizumab and trastuzumab in HER2-positive oesophageal, gastric, or gastro-oesophageal junction cancer: an open-label, single-arm, phase 2 trial.
Janjigian, Yelena Y; Maron, Steven B; Chatila, Walid K; Millang, Brittanie; Chavan, Shweta S; Alterman, Carly; Chou, Joanne F; Segal, Michal F; Simmons, Marc Z; Momtaz, Parisa; Shcherba, Marina; Ku, Geoffrey Y; Zervoudakis, Alice; Won, Elizabeth S; Kelsen, David P; Ilson, David H; Nagy, Rebecca J; Lanman, Richard B; Ptashkin, Ryan N; Donoghue, Mark T A; Capanu, Marinela; Taylor, Barry S; Solit, David B; Schultz, Nikolaus; Hechtman, Jaclyn F.
Afiliação
  • Janjigian YY; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. Electronic address: janjigiy@mskcc.org.
  • Maron SB; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
  • Chatila WK; Marie-Josée & Henry R Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Tri-Institutional Program in Computational Biology and Medicine, Weill Cornel
  • Millang B; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chavan SS; Marie-Josée & Henry R Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Alterman C; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chou JF; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Segal MF; Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Simmons MZ; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Momtaz P; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Shcherba M; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ku GY; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
  • Zervoudakis A; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Won ES; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
  • Kelsen DP; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
  • Ilson DH; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.
  • Nagy RJ; Guardant Health, Redwood City, CA, USA.
  • Lanman RB; Guardant Health, Redwood City, CA, USA.
  • Ptashkin RN; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Donoghue MTA; Marie-Josée & Henry R Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Capanu M; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Taylor BS; Marie-Josée & Henry R Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Solit DB; Marie-Josée & Henry R Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New Y
  • Schultz N; Marie-Josée & Henry R Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Canc
  • Hechtman JF; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lancet Oncol ; 21(6): 821-831, 2020 06.
Article em En | MEDLINE | ID: mdl-32437664

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Neoplasias Esofágicas / Adenocarcinoma / Protocolos de Quimioterapia Combinada Antineoplásica / Receptor ErbB-2 / Junção Esofagogástrica / Anticorpos Monoclonais Humanizados / Trastuzumab / Antineoplásicos Imunológicos País/Região como assunto: America do norte Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Neoplasias Esofágicas / Adenocarcinoma / Protocolos de Quimioterapia Combinada Antineoplásica / Receptor ErbB-2 / Junção Esofagogástrica / Anticorpos Monoclonais Humanizados / Trastuzumab / Antineoplásicos Imunológicos País/Região como assunto: America do norte Idioma: En Ano de publicação: 2020 Tipo de documento: Article