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Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization.
Banga, Jaspreet; Srinivasan, Dinesh; Sun, Chia-Chi; Thompson, Cherrie D; Milletti, Francesca; Huang, Kuo-Sen; Hamilton, Shannon; Song, Su; Hoffman, Ann F; Qin, Yajuan Gu; Matta, Bharati; LaPan, Margaret; Guo, Qin; Lu, Gang; Li, Dan; Qian, Hong; Bolin, David R; Liang, Lena; Wartchow, Charles; Qiu, Jin; Downing, Michelle; Narula, Satwant; Fotouhi, Nader; DeMartino, Julie A; Tan, Seng-Lai; Chen, Gang; Barnes, Betsy J.
Afiliação
  • Banga J; The Feinstein Institute for Medical Research, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, 350 Community Dr., Manhasset, NY 11030, USA.
  • Srinivasan D; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Sun CC; EMD Serono Research and Development Institute Inc., 45A Middlesex Turnpike, Billerica, MA 01821, USA.
  • Thompson CD; The Feinstein Institute for Medical Research, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, 350 Community Dr., Manhasset, NY 11030, USA.
  • Milletti F; Roche Innovation Center New York, 430 East 29th Street, New York, NY 10016, USA.
  • Huang KS; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Hamilton S; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Song S; The Feinstein Institute for Medical Research, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, 350 Community Dr., Manhasset, NY 11030, USA.
  • Hoffman AF; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Qin YG; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Matta B; The Feinstein Institute for Medical Research, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, 350 Community Dr., Manhasset, NY 11030, USA.
  • LaPan M; The Feinstein Institute for Medical Research, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, 350 Community Dr., Manhasset, NY 11030, USA.
  • Guo Q; The Feinstein Institute for Medical Research, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, 350 Community Dr., Manhasset, NY 11030, USA.
  • Lu G; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Li D; The Feinstein Institute for Medical Research, Center for Autoimmune, Musculoskeletal and Hematopoietic Diseases, 350 Community Dr., Manhasset, NY 11030, USA.
  • Qian H; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Bolin DR; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Liang L; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Wartchow C; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Qiu J; EMD Serono Research and Development Institute Inc., 45A Middlesex Turnpike, Billerica, MA 01821, USA.
  • Downing M; EMD Serono Research and Development Institute Inc., 45A Middlesex Turnpike, Billerica, MA 01821, USA.
  • Narula S; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Fotouhi N; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • DeMartino JA; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Tan SL; EMD Serono Research and Development Institute Inc., 45A Middlesex Turnpike, Billerica, MA 01821, USA.
  • Chen G; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
  • Barnes BJ; Hoffmann-La Roche Inc., 340 Kingsland Street, Nutley, NJ 07110, USA.
Sci Adv ; 6(20): eaay1057, 2020 05.
Article em En | MEDLINE | ID: mdl-32440537

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Penetradores de Células Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Penetradores de Células Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos