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Phase and context shape the function of composite oncogenic mutations.
Gorelick, Alexander N; Sánchez-Rivera, Francisco J; Cai, Yanyan; Bielski, Craig M; Biederstedt, Evan; Jonsson, Philip; Richards, Allison L; Vasan, Neil; Penson, Alexander V; Friedman, Noah D; Ho, Yu-Jui; Baslan, Timour; Bandlamudi, Chaitanya; Scaltriti, Maurizio; Schultz, Nikolaus; Lowe, Scott W; Reznik, Ed; Taylor, Barry S.
Afiliação
  • Gorelick AN; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Sánchez-Rivera FJ; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Cai Y; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Bielski CM; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Biederstedt E; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Jonsson P; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Richards AL; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Vasan N; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Penson AV; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Friedman ND; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ho YJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Baslan T; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Bandlamudi C; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Scaltriti M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Schultz N; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Reznik E; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Taylor BS; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nature ; 582(7810): 100-103, 2020 06.
Article em En | MEDLINE | ID: mdl-32461694

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oncogenes / Carcinogênese / Modelos Genéticos / Mutação / Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oncogenes / Carcinogênese / Modelos Genéticos / Mutação / Neoplasias Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos