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A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites.
Reich, Stefan; Nguyen, Chi D L; Has, Canan; Steltgens, Sascha; Soni, Himanshu; Coman, Cristina; Freyberg, Moritz; Bichler, Anna; Seifert, Nicole; Conrad, Dominik; Knobbe-Thomsen, Christiane B; Tews, Björn; Toedt, Grischa; Ahrends, Robert; Medenbach, Jan.
Afiliação
  • Reich S; Biochemistry I, University of Regensburg, Regensburg, Germany.
  • Nguyen CDL; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany.
  • Has C; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany.
  • Steltgens S; Institute for Clinical Chemistry and Laboratory Medicine, Technical University Dresden, Dresden, Germany.
  • Soni H; Department of Neuropathology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Coman C; Molecular Mechanisms of Tumor Invasion, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Freyberg M; Department of Analytical Chemistry, University of Vienna, Vienna, Austria.
  • Bichler A; Biochemistry I, University of Regensburg, Regensburg, Germany.
  • Seifert N; Biochemistry I, University of Regensburg, Regensburg, Germany.
  • Conrad D; Biochemistry I, University of Regensburg, Regensburg, Germany.
  • Knobbe-Thomsen CB; Biochemistry I, University of Regensburg, Regensburg, Germany.
  • Tews B; Department of Neuropathology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
  • Toedt G; Molecular Mechanisms of Tumor Invasion, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Ahrends R; AbbVie Deutschland GmbH & Co.KG, Wiesbaden, Germany.
  • Medenbach J; Computational Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Nat Commun ; 11(1): 2936, 2020 06 10.
Article em En | MEDLINE | ID: mdl-32522993

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulon / Resposta a Proteínas não Dobradas / Ácido Fólico / Antimetabólitos Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulon / Resposta a Proteínas não Dobradas / Ácido Fólico / Antimetabólitos Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha