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The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma.
Crawford, Lisa J; Campbell, David C; Morgan, Jonathan J; Lawson, Michelle A; Down, Jennifer M; Chauhan, Dharminder; McAvera, Roisin M; Morris, Treen C; Hamilton, Claudia; Krishnan, Aswini; Rajalingam, Krishnaraj; Chantry, Andrew D; Irvine, Alexandra E.
Afiliação
  • Crawford LJ; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK. lisa.crawford@qub.ac.uk.
  • Campbell DC; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Morgan JJ; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Lawson MA; Department of Oncology and Metabolism, Sheffield Myeloma Research Team, Medical School, University of Sheffield, Sheffield, UK.
  • Down JM; Department of Oncology and Metabolism, Sheffield Myeloma Research Team, Medical School, University of Sheffield, Sheffield, UK.
  • Chauhan D; Department of Medical Oncology, The LeBow Institute for Myeloma Therapeutics and Jerome Lipper Myeloma Center, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • McAvera RM; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Morris TC; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Hamilton C; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Krishnan A; Cell Biology Unit, University Medical Center Mainz, Mainz, Germany.
  • Rajalingam K; Cell Biology Unit, University Medical Center Mainz, Mainz, Germany.
  • Chantry AD; Department of Oncology and Metabolism, Sheffield Myeloma Research Team, Medical School, University of Sheffield, Sheffield, UK.
  • Irvine AE; Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
Oncogene ; 39(27): 5001-5014, 2020 07.
Article em En | MEDLINE | ID: mdl-32523091
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Proteínas Proto-Oncogênicas c-myc / Proteínas Supressoras de Tumor / Ubiquitina-Proteína Ligases / Lenalidomida / Mieloma Múltiplo / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Proteínas Proto-Oncogênicas c-myc / Proteínas Supressoras de Tumor / Ubiquitina-Proteína Ligases / Lenalidomida / Mieloma Múltiplo / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido