Jejunal villus absorption and paracellular tight junction permeability are major routes for early intestinal uptake of food-grade TiO<sub>2</sub> particles: an in vivo and ex vivo study in mice.

Coméra, Christine; Cartier, Christel; Gaultier, Eric; Catrice, Olivier; Panouille, Quentin; El Hamdi, Sarah; Tirez, Kristof; Nelissen, Inge; Théodorou, Vassilia; Houdeau, Eric

Jejunal villus absorption and paracellular tight junction permeability are major routes for early intestinal uptake of food-grade TiO₂ particles: an in vivo and ex vivo study in mice.

Coméra, Christine; Cartier, Christel; Gaultier, Eric; Catrice, Olivier; Panouille, Quentin; El Hamdi, Sarah; Tirez, Kristof; Nelissen, Inge; Théodorou, Vassilia; Houdeau, Eric.

Afiliação

Coméra C; Toxalim (Research Centre in Food Toxicology), Toulouse University, INRAE, ENVT, INP, Toulouse, France. Christine.comera@inrae.fr.
Cartier C; Toxalim (Research Centre in Food Toxicology), Toulouse University, INRAE, ENVT, INP, Toulouse, France.
Gaultier E; Toxalim (Research Centre in Food Toxicology), Toulouse University, INRAE, ENVT, INP, Toulouse, France.
Catrice O; LIPM, Université de Toulouse, INRAE, CNRS, Castanet-Tolosan, France.
Panouille Q; Toxalim (Research Centre in Food Toxicology), Toulouse University, INRAE, ENVT, INP, Toulouse, France.
El Hamdi S; Toxalim (Research Centre in Food Toxicology), Toulouse University, INRAE, ENVT, INP, Toulouse, France.
Tirez K; VITO (Flemish Institute for Technological Research), Mol, Belgium.
Nelissen I; VITO (Flemish Institute for Technological Research), Mol, Belgium.
Théodorou V; Toxalim (Research Centre in Food Toxicology), Toulouse University, INRAE, ENVT, INP, Toulouse, France.
Houdeau E; Toxalim (Research Centre in Food Toxicology), Toulouse University, INRAE, ENVT, INP, Toulouse, France.

Part Fibre Toxicol ; 17(1): 26, 2020 06 11.

Article em En | MEDLINE | ID: mdl-32527323

Assuntos

Mucosa Intestinal/metabolismo; Jejuno/metabolismo; Microvilosidades/metabolismo; Nanopartículas/administração & dosagem; Junções Íntimas/metabolismo; Titânio/farmacocinética; Animais; Transporte Biológico; Exposição Dietética; Absorção Intestinal; Camundongos Endogâmicos C57BL; Tamanho da Partícula; Permeabilidade; Distribuição Tecidual; Titânio/administração & dosagem

Palavras-chave

Food additive; Intestinal absorption; Nanoparticles; Titanium dioxide

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Titânio / Junções Íntimas / Nanopartículas / Mucosa Intestinal / Jejuno / Microvilosidades Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: França

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