Towards electroenzymatic processes involving old yellow enzymes and mediated cofactor regeneration.
Eng Life Sci
; 17(1): 71-76, 2017 Jan.
Article
em En
| MEDLINE
| ID: mdl-32624730
ABSTRACT
Old yellow enzymes are able to catalyze asymmetric C=C reductions. A mediated electroenzymatic process to regenerate the NADPH in combination with an old yellow enzyme was investigated. Due to the fact that the overall process was affected by a broad set of parameters, a design of experiments (DoE) approach was chosen to identify suitable process conditions. Process conditions with high productivities of up to 2.27 mM/h in combination with approximately 90% electron transfer efficiency were identified.
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MEDLINE
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En
Ano de publicação:
2017
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Article