ATM mutations as an independent prognostic factor and potential biomarker for immune checkpoint therapy in endometrial cancer.

Sun, Lei; Wang, Run-Chang; Zhang, Qing; Guo, Lin-Lang

Sun, Lei; Wang, Run-Chang; Zhang, Qing; Guo, Lin-Lang.

Afiliação

Sun L; Department of Pathology, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510282, China.
Wang RC; Second Clinical School, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Road, Wuhan 430030, China.
Zhang Q; Second Clinical School, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Road, Wuhan 430030, China. Electronic address: Qing--Zhang@hotmail.com.
Guo LL; Department of Pathology, Zhujiang Hospital, Southern Medical University, 253 Gongye Road, Guangzhou 510282, China. Electronic address: linlangg@yahoo.com.

Pathol Res Pract ; 216(8): 153032, 2020 Aug.

Article em En | MEDLINE | ID: mdl-32703496

Assuntos

Proteínas Mutadas de Ataxia Telangiectasia/genética; Biomarcadores Tumorais/genética; Neoplasias do Endométrio/genética; Microambiente Tumoral/imunologia; Adulto; Idoso; Idoso de 80 Anos ou mais; Biomarcadores Tumorais/imunologia; Biologia Computacional; Análise Mutacional de DNA; Neoplasias do Endométrio/imunologia; Neoplasias do Endométrio/patologia; Feminino; Humanos; Inibidores de Checkpoint Imunológico; Linfócitos do Interstício Tumoral; Pessoa de Meia-Idade; Mutação; Prognóstico

Palavras-chave

ATM mutations; Bioinformatics; Endometrial cancer; Immune infiltration; Prognosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Neoplasias do Endométrio / Microambiente Tumoral / Proteínas Mutadas de Ataxia Telangiectasia Idioma: En Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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