BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts.

Yahiro, Yuhei; Maeda, Shingo; Morikawa, Masato; Koinuma, Daizo; Jokoji, Go; Ijuin, Toshiro; Komiya, Setsuro; Kageyama, Ryoichiro; Miyazono, Kohei; Taniguchi, Noboru

Yahiro, Yuhei; Maeda, Shingo; Morikawa, Masato; Koinuma, Daizo; Jokoji, Go; Ijuin, Toshiro; Komiya, Setsuro; Kageyama, Ryoichiro; Miyazono, Kohei; Taniguchi, Noboru.

Afiliação

Yahiro Y; Department of Orthopaedic Surgery, Kagoshima University, Kagoshima, Kagoshima 890-8520 Japan.
Maeda S; Department of Medical Joint Materials, Kagoshima University, Kagoshima, Kagoshima 890-8520 Japan.
Morikawa M; Department of Medical Joint Materials, Kagoshima University, Kagoshima, Kagoshima 890-8520 Japan.
Koinuma D; Department of Bone and Joint Medicine, Kagoshima University, Kagoshima, Kagoshima 890-8520 Japan.
Jokoji G; Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033 Japan.
Ijuin T; Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033 Japan.
Komiya S; Department of Orthopaedic Surgery, Kagoshima University, Kagoshima, Kagoshima 890-8520 Japan.
Kageyama R; Department of Medical Joint Materials, Kagoshima University, Kagoshima, Kagoshima 890-8520 Japan.
Miyazono K; Department of Bone and Joint Medicine, Kagoshima University, Kagoshima, Kagoshima 890-8520 Japan.
Taniguchi N; Department of Orthopaedic Surgery, Kagoshima University, Kagoshima, Kagoshima 890-8520 Japan.