Rebellious autophagy proteins bypass ATG8 lipidation, taking their own path to autophagic degradation.
EMBO J
; 39(24): e106990, 2020 12 15.
Article
em En
| MEDLINE
| ID: mdl-33226132
ABSTRACT
LC3/GABARAP (hereafter ATG8) conjugation machineries have long been thought to play an essential role in autophagy by driving ATG8 lipidation on autophagosomal membranes. In this issue, Ohnstad et al (2020) describe an ATG8 lipidation bypass pathway which governs autophagy-dependent turnover of NBR1, highlighting that there is more than one road to autophagic degradation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Autofagia
/
Proteínas Associadas aos Microtúbulos
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Austrália