The Chiron Approach to (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol, a Key Subunit of HIV-1 Protease Inhibitor Drug, Darunavir.

Ghosh, Arun K; Markad, Shivaji B; Robinson, William L

Ghosh, Arun K; Markad, Shivaji B; Robinson, William L.

Afiliação

Ghosh AK; Department of Chemistry and Department of Medicinal Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.
Markad SB; Department of Chemistry and Department of Medicinal Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.
Robinson WL; Department of Chemistry and Department of Medicinal Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States.

J Org Chem ; 86(1): 1216-1222, 2021 01 01.

Article em En | MEDLINE | ID: mdl-33267583

Assuntos

Inibidores da Protease de HIV; HIV-1; Preparações Farmacêuticas; Darunavir; Furanos; Inibidores da Protease de HIV/farmacologia; Humanos; Estereoisomerismo; Vacinas Virais

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / HIV-1 / Inibidores da Protease de HIV Idioma: En Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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